The Dandelion Dilemma Revisited for Oligoprogression: Treat the Whole Lawn or Weed Selectively?

When early-stage metastases appear, what is the evidence comparing the utility of systemic drug treatment versus focused radiation? "Oligoprogressive disease is a relatively new clinical concept describing progression at only a few sites of metastasis in patients with otherwise controlled widespread disease. Local ablative therapy for oligoprogressive disease may allow the continuation of systemic treatments by overcoming the few sub-clones that have developed resistance." READ ARTICLE

Clinical Oncology; DOI: 10.1016/j.clon.2019.05.015;

Authors: P.H. Patel, D. Palma, F. McDonald, A.C. Tree

Review PaperKirk SmithDecember 1, 2019metastatic disease, Oligometastases, oligoprogression, stereotactic body radiotherapy, targeted therapy