When early-stage metastases appear, what is the evidence comparing the utility of systemic drug treatment versus focused radiation? "Oligoprogressive disease is a relatively new clinical concept describing progression at only a few sites of metastasis in patients with otherwise controlled widespread disease. Local ablative therapy for oligoprogressive disease may allow the continuation of systemic treatments by overcoming the few sub-clones that have developed resistance." Read Article
Clinical Oncology; DOI Number: 10.1016/j.clon.2019.05.015;
Authors: P.H. Patel, D. Palma, F. McDonald, A.C. Tree