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Tag: TKI

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    Grapefruit & TKIs

    A Review: Interview with Dr. Lin, Does Grapefruit Interfere with TKIs? The interview with Dr. Lin covered topics that we should know about with regards to cytochrome P450 and its significance in processing TKI* medication. Cytochrome P450 is part of a system important in metabolizing medicine in the liver. Cytochromes metabolize oily (fat-soluble) chemicals so they…

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  • How do ALK TKIs affect pregnancy?

    Studies on ALK TKIs* and Pregnancy In 2016, there was a study reported by Dr. Ibiayi et. al. (Dr. Shaw’s group) on patients who were pregnant or had just given birth to a child while diagnosed with NSCLC (non-small cell lung cancer) between 2009 and 2015.  They identified 2422 women with lung cancer of whom…

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