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WE NEED YOUR INFO: Take part in our longitudinal survey of ALK+ Cancer Patients
More participants = more data = better research = more life!We invite you to complete a patient survey/registry specific to ALK-positive lung cancer. This is an IRB approved professionally study conducted by researchers at University of Washington and paid for by ALK Positive Inc. All data is de-identified, and will inform oncologists, researchers, patients and…
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The New ALK Inhibitor: NVL-655 Expands Clinical Trial Sites
Who is this trial for: NVL-655 is a 4th generation, brain-penetrant, ALK TKI inhibitor created to overcome several limitations observed with currently available therapies. NVL-655 is designed to have activity in tumors that have developed resistance to first, second, and third-generation ALK inhibitors, including tumors with the solvent front G1202R mutation or compound mutations G1202R/L1196M…
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Hearty Fall Vegetable Soup Recipe by Chef and Fellow ALKie, Juli Posner
With the cold weather upon us ( and the holidays right around the corner), I love making a one-pot meal that’s great the “day of”, and only gets better day-by-day….. That is, if your family doesn’t devour it in one sitting! Having it be super healthy is an extra added bonus! For this soup, which is…
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PATIENT SPOTLIGHT: Debbi Martinez, New Jersey, USA
Member and fellow ALKie Debbi Martinez is the volunteer working behind the scenes with ALK Positive’s Kindful fundraising platform and doing a great job at that. For this year’s Lung Cancer Awareness Month, we wanted to honor a volunteer that is not visible by being at the forefront of operations, but is just as invaluable…
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ALK+ Summit 2022 in Denver, CO was largest Summit yet!!
Date: July 29th-31st Attendees: in-person: 250 Virtual: 850 The ALK Positive annual summit was once again a huge success! This year the event was held both in Denver, Colorado and virtually (online). We had 250 individual registrations in-person and 850 virtual attendees. Our ALK Summit in Denver was a great opportunity to…
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Dr. Kenneth Culver named Director of Research & Clinical Affairs for ALK Positive Inc.
We are excited to welcome Dr. Kenneth Culver as our first Director of Research & Clinical Affairs! Dr. Culver graduated from the University of Iowa College of Medicine in 1981. He completed his internship and residency in Pediatrics and a fellowship in Pediatric immunology at the University of California, San Francisco. At UCSF, he developed…
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Pre-Clinical Research Sets the Stage for Clinical Trials
Clinical trials are studies that are done in humans to test a new treatment. Long before a clinical trial, a host of “pre-clinical” studies must test the feasibility, safety, and effectiveness of a new treatment. Preliminary work involves chemistry to develop a compound that can be manufactured and has the potential to inhibit cancer growth.…
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Phase 1 Clinical Trial NCT05346494 by Imugene Limited
VAXINIA study of CF33-hNIS, an oncolytic virus, as monotherapy or in combination with Pembrolizumab, in adults with metastatic or advanced solid tumors (MAST), including NSCLC: Check ClinicalTrials.gov Imugene’s CF33, or Vaxinia, is a modified DNA virus of the Poxviridae family developed by Professor Yuman Fong at the City of Hope Comprehensive Cancer Center in Los…
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Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer
by Mizuta et al. (Japan) A common problem that we face is that cancer becomes resistant to our TKIs (Crizotinib, Brigatinib, Alectinib, Ceritinib, and Lorlatinib) over time. There are two known mechanisms of resistance so far. One is for the cancer cells to activate an alternative bypass pathway such as EGFR, cMET, KRAS, or AXL…
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PATIENT SPOTLIGHT: Ruby Blow, Atlanta, GA, USA
Please enjoy our interview with the wonderful and courageous Ruby Blow! 1) Share with us a little bit about yourself, including your personal life, your professional background, and your journey with lung cancer so far. I am a sister, an aunt, and a professional counselor. I have my own practice. I stopped seeing therapy clients,…
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Butternut Squash, Spinach, and Spicy Sausage Soup with Orzo Recipe
This comforting soup makes a delicious and savory soup that’s perfect for those cold busy nights in the Fall and Winter when butternut squash is also in season. *feel free to substitute sweet pork sausage in this recipe if spicy isn’t your thing! One pot – 30 minutes start to finish!
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A New Clinical Trial in Italy: Does Supervised Exercise Improve Outcomes in Oncogene Addicted Lung Cancer?
For those diagnosed with advanced lung cancer, there is often the question of how lifestyle changes can improve the prognosis. A unique study in Italy called EXcellenT will measure how supervised exercise affects outcomes. Those who have a positive biomarker, like ALK, can participate if they are on their first or second tyrosine kinase inhibitor…