Posts tagged mutation–mediated
Acquired Exon 14 MET Mutation Associated With Resistance to Alectinib in a Patient With ALK–Rearranged NSCLC

As far as we are aware, this present clinical case is the first to report an acquired exon14 MET mutation
mediated resistance to alectinib in a patient with ALK rearrangement NSCLC. We had chosen to treat
our patient at the time of progression under alectinib with crizotinib with a short time efficacy, three and a
half months. READ ARTICLE

JTO Clinical and Research Reports DOI:10.1016/j.jtocrr.2020.100082

Authors: Catherine Daniel, Celine Callens, Samia Melaabi, Ivan Bieche, Nicolas Girard,

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