EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation

Our data suggest that the aberrant expression of EML4-ALK leads to JAK2-STAT signaling pathway activation, which is essential for the development of non-small cell lung cancer. READ ARTICLE

BMC Pulmonary Medicine DOI:10.1186/s12890-021-01553-z

Authors: Ying Li, Yongwen Li, Hongbing Zhang, Ruifeng Shi, Zihe Zhang, Hongyu Liu, and Jun Chen

Pre-Clinical, group5Kirk SmithJune 6, 2021EML4-ALK, JAK2-STAT pathway, Non-small cell lung cancer (NSCLC), Transformation

EML4-ALK-mediated Activation of the JAK2-STAT Pathway is Critical for Non-small Cell Lung Cancer Transformation

Aberrant expression of EML4-ALK leads to JAK2-STAT signaling pathway activation, an essential part of the development of non-small cell lung cancer. READ ARTICLE

BMC Pulmonary Medicine DOI: https://doi.org/10.1186/s12890-021-01553-z

Authors: Ying Li, Yongwen Li, Hongbing Zhang, Ruifeng Shi, Zihe Zhang, Hongyu Liu, Jun Chen

Pre-ClinicalKirk SmithDecember 1, 2020EML4-ALK, JAK2-STAT pathway, transformation, NSCLC