Practical management of major Lorlatinib side effects

Side effects are color-coded for blood (yellow), cognitive effects (green), and other common seen effects (purple). 

Lorlatinib_SideEffects_Slide1.png
Lorlatinib_SideEffects_Slide2.png


There are other side effects noted by oncologists but the ones in the chart are the most common ones. 

This is a link to the safety data sheet for Lorlatinib. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210868s000lbl.pdf

If you are interested in seeing all reported side effects, go to p4-9.  

Avoid Lorlatinib with any CYP3A inducers. 

https://www.sciencedirect.com/science/article/pii/S1040842820301074

Kirk Smith