Background: ROS proto-oncogene 1 (ROS1) rearrangements are a known molecular target in non–small-cell lung cancer (NSCLC). Our goal was to determine whether ROS1-rearranged NSCLC has imaging features and patterns of metastasis, which differ from those of anaplastic lymphoma kinase (ALK)-rearranged or epidermal growth factor receptor (EGFR)-mutant NSCLC... Conclusion: Although considerable overlap exists in the imaging features of ROS1-rearranged, ALK-rearranged, and EGFR-mutant NSCLC, we found that ROS1-rearranged NSCLC has certain distinct imaging features and patterns of spread. READ ARTICLE
Clinical Lung Cancer DOI:10.1016/j.cllc.2019.10.006
Authors: Subba R. Digumarthy, Dexter P. Mendoza, Jessica J. Lin, Tianqi Chen, Marguerite M. Rooney, Emily Chin, Lecia V. Sequist, Jochen K. Lennerz, Justin F. Gainor, Alice T. Shaw
