"ALK rearrangements are an established targetable oncogenic driver in non–small cell lung cancer (NSCLC). The goal of this study was to determine the imaging features of the primary tumor and metastatic patterns in advanced ALK-rearranged (ALK+) NSCLC that may be different from those in EGFR-mutant (EGFR+) or EGFR/ALK wild-type (EGFR−/ALK−) NSCLC. CONCLUSION. Advanced ALK+ NSCLC has primary tumor imaging features and patterns of metastasis that are different from those of EGFR+ or EGFR−/ALK− wild type NSCLC at the time of initial presentation. READ ARTICLE
American Journal of Roentgenology DOI:10.2214/AJR.19.21982
Authors: Dexter P. Mendoza, Jessica J. Lin, Marguerite M. Rooney, Tianqi Chen, Lecia V. Sequist, Alice T. Shaw, Subba R. Digumarthy"