Adequacy of EBUS-TBNA specimen for mutation analysis of lung cancer

Convex probe endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) is a minimally invasive technique with high sensitivity in the mediastinal staging of non-small cell carcinoma (NSCLC). The aim of this study was to evaluate the adequacy of EBUS-TBNA in providing adequate size specimens for EGFR, ALK and ROS1 genetic mutation analysis in patients with adenocarcinoma or not otherwise specified (NOS) lung cancer.
The study demonstrated that EBUS-TBNA provides adequate material for mutation analysis in patients with newly diagnosed adenocarcinoma or NOS lung cancer. READ ARTICLE

The Clinical Respiratory Journal DOI:10.1111/crj.12985

Authors: Tugba Cicek, Ayperi Ozturk, Aydın Yılmaz, Zafer Aktas, Funda Demirag, Nalan Akyurek