What do you know about clinical trials? Take this test to find out.

Question 1: There are clinical trials for people at all stages of treatment—even at diagnosis.

True. Clinical trials are not just for people who have exhausted all options. Many trials are specifically designed for people who are newly diagnosed or early in their treatment. In ALK-positive lung cancer, some trials study whether newer targeted therapies work better or longer than current standard treatments when used first.

Question 2: Many clinical trials use a placebo as the main cancer treatment.

False. In cancer clinical trials, patients are not left untreated. When a placebo is used, it is typically added on top of standard-of-care treatment, not given alone. Everyone in the trial receives appropriate cancer care, and no one is denied effective therapy.

Question 3: Your oncologist will always recommend a clinical trial if you qualify.

False. While oncologists want the best for their patients, it’s impossible for any single doctor to know about every available clinical trial. Trials open and close frequently and may be located at other institutions. This is why patients often need to ask about trials, seek second opinions, or work with patient advocacy groups to explore all options.

Question 4: A clinical trial will cover the cost of all your treatment, including travel.

False.

Clinical trials typically cover:

· The experimental drug or treatment

· Any extra visits, labs, scans, or procedures required only because of the trial

Your insurance usually covers standard-of-care costs, such as routine clinic visits, labs, and imaging you would receive even if you were not in a trial. Some trials offer help with travel expenses, but many do not. The ALK Positive website lists organizations that may help with travel and lodging costs for eligible patients.

Question 5: A clinical trial will treat me like a guinea pig.

False. All cancer treatment is individualized. Even outside of clinical trials, doctors often adjust medications, doses, and schedules based on how a patient responds and what side effects occur. In that sense, cancer care always involves careful trial and adjustment. Clinical trials simply study treatments in a structured, closely monitored, and highly regulated way, with strong patient protections and oversight.

Question 6: Clinical trials tend to involve more visits and scans.

True. Most clinical trials involve closer monitoring, especially early on. This may mean more frequent visits, blood tests, or imaging. Some patients find this reassuring because issues can be identified quickly. However, trial visits and scans usually must be done at the trial site, and flexibility is often limited.

Question 7: A clinical trial is very risky.

False. All treatments—standard or experimental—carry some level of risk. Clinical trials are designed in phases to evaluate safety step by step, and patients are closely monitored throughout. Trials also have strict rules for stopping or modifying treatment if safety concerns arise. Many people assume trials are more dangerous, but standard treatments also come with known and unknown risks.

Question 8: A clinical trial must be close to your home.

False. Many clinical trials are conducted at major cancer centers and may require travel. While this can be a barrier, distance alone does not disqualify someone from participating. Some patients travel for trials because they feel the potential benefits outweigh the inconvenience, and financial assistance may be available. You may still have visits with your local oncologist to remain connected to your provider, as long as any treatment changes are reviewed with the clinical trial physician.

Question 9: You can leave a clinical trial at any time if it is no longer right for you.

True. Participation in a clinical trial is always voluntary. You can choose to leave a trial at any time and for any reason—whether due to side effects, logistics, or a change in personal priorities.

Leaving a trial does not mean you lose access to medical care. Your oncology should help transition you to another appropriate treatment.

Question 10: Joining a clinical trial means you won’t know which treatment you are receiving.

False. Most cancer clinical trials are not blinded, meaning both you and your doctor know which treatment you are receiving. Even in studies that involve randomization, the treatments are clearly explained during the informed consent process, and patients are never kept in the dark about their care.

How did you do on this quiz?

Clinical trials have paved the way for better treatment and longer survival for ALK-Positive lung cancer. There may be a trial that’s right for you.

Clinical Trials Currently Recruiting for ALK-positive Cancers.

General Information About Clinical Trials

By Ellee Urban